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Current trends in biocompatibility testing

1998

Biocompatibility remains the central theme for biomaterials applications in medicine. It is generally accepted that this term means not only absence of a cytotoxic effect but also positive effects in the sense of biofunctionality, i.e. promotion of biological processes which further the intended aim of the application of a biomaterial. The national and international standards for testing regimes represent a lowest common denominator for such applications and do not necessarily ensure that optimal function will be achieved. The authors' thesis is that biocompatibility testing has scope for extensive development with respect to biofunctionality. The present paper reviews current trends in the…

In Vitro TechniquesBiocompatibilitymedia_common.quotation_subjectCytological TechniquesBiocompatible MaterialsNanotechnologyIn Vitro TechniquesBiologyOrgan development03 medical and health sciences0302 clinical medicineMaterials TestingCell AdhesionMedical Laboratory ScienceAnimalsHumansLowest common denominatorFunction (engineering)Cells Culturedmedia_commonScope (project management)Mechanical EngineeringBiocompatibility TestingReproducibility of ResultsGeneral MedicineCytotoxicity Tests ImmunologicCritical appraisalRisk analysis (engineering)030220 oncology & carcinogenesisStress MechanicalRheology030217 neurology & neurosurgeryForecastingProceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
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